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Home / Primary Antibodies / Polyclonal Antibodies

AMPK gamma 1 antibody

SKU : BHA10800374

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Mfr.No.	FNab00379
Alternative Names	AMPKgamma1 ; AMPKsubunitgamma1 ; AMPKG ; PRKAG1
Background	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Categories	Primary Antibodies
Cellular Localization	Cytosol, Embrane, Ucleoplasm
Clonality	polyclonal
Description	Protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1, synonyms: AMPKG, MGC8666) is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an catalytic subunit, and non-catalytic and subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and -hydroxy-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK.
Host	Rabbit
Immunogen	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Isotype	IgG
Molecular Weight	38 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	cytosol,nucleoplasm,membrane
Synonyms	AMPK gamma1, AMPK subunit gamma 1, AMPKG, PRKAG1

Uniprot	P54619
Gene Id	5571
Research Area	Developmental biology, Cardiovascular, Metabolism, Signal Transduction
Weight	38kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab00379.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800374	FNab00379	100ug	$240		Add to Cart

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