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Home / Primary Antibodies / Polyclonal Antibodies

AMPK gamma 1 antibody

SKU : BHA10810292

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Mfr.No.	FNab10337
Background	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Clonality	polyclonal
Host	Rabbit
Immunogen	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Immunogen Region	protein kinase, AMP-actIVated, gamma 1 non-catalytic subunit
Isotype	IgG
Molecular Weight	35-40 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500 - 1:2000
Subcellular Location	cytosol,nucleoplasm,membrane
Synonyms	AMPK gamma1, AMPK subunit gamma 1, AMPKG, PRKAG1

Uniprot	P54619
Gene Id	5571
Research Area	Developmental biology, Cardiovascular, Metabolism, Signal Transduction

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:2000

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10337.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810292	FNab10337	100ug	$240		Add to Cart

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