Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).
Categories
Primary Antibodies
Cellular Localization
Mitochondria, Xtracellular Exosome, Ytosol
Clonality
polyclonal
Description
Fructose-bisphosphate aldolase C (ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).
Host
Rabbit
Immunogen
aldolase C, fructose-bisphosphate
Isotype
IgG
Molecular Weight
39 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
mitochondrion,cytosol,extracellular exosome
Synonyms
ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C
Antigen
Aldolase C
Uniprot
P09972
Gene Id
230
Research Area
Metabolism
Weight
39kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)