Rabbit Anti-Human AKT1 Polyclonal

Mfr.No.	SPC-789, SPC-789D, SPC-789D-A390, SPC-789D-A488, SPC-789D-A594, SPC-789D-ALP, SPC-789D-APC, SPC-789D-BI, SPC-789D-FITC, SPC-789D-HRP, SPC-789D-PCP, SPC-789D-RPE, SPC-789S
Immunogen Species	Human
Alternative Names	RAC-alpha serine/threonine-protein kinase Antibody, Protein Kinase B Alpha Antibody, EC:2.7.11.1 Antibody, AKT1 Antibody, AKT Antibody, MGC99656 Antibody, PKB alpha Antibody, PKB-ALPHA Antibody, AKT 1 Antibody, RAC-PK-alpha Antibody, PRKBA Antibody, PKB Antibody, Protein kinase B alpha Antibody, Protein kinase B Antibody, Proto-oncogene c-Akt Antibody, AKT1_HUMAN Antibody, RAC Antibody, RAC Alpha Antibody
Categories	Antibodies
Cellular Localization	Cytoplasm, Nucleus, Cell Membrane
Certificate Of Analysis	A 1:1000 dilution of SPC-789 was sufficient for detection of AKT1 in 15 ug of rat Liver cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human AKT1 Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide from the N-terminal of Human RAC-alpha serine/threonine-protein kinase (aa. 1-100), Homo Sapiens (Human)
Immunogen Region	Synthetic peptide from the N-terminal of Human RAC-alpha serine/threonine-protein kinase (aa. 1-100)
Launch Date	2018/03/09
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Rat, Human
Tissue Specificity	Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.

Swissprot	P31749
Accession Number	NP_001014431.1
Gene Id	207
Target	AKT1
Research Area	Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases, PKB / AKT, Metabolism, Metabolism processes, Epigenetics and Nuclear Signaling, Cancer, Apoptosis

Buffer	PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Concentration	1 mg/ml
Dilutions	WB (1:1000); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 55 kDa.
Storage	-20ºC
Storage Buffer	PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	IHC, WB
Description	WB
Dilution	WB (1:1000); IHC (1:50); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11910807-1	SPC-789D	Unconjugated	100 ug	$330	Add to Cart
BHA11910807-2	SPC-789D-A390	ATTO 390	100 ug	$384	Add to Cart
BHA11910807-3	SPC-789D-A488	ATTO 488	100 ug	$383	Add to Cart
BHA11910807-4	SPC-789D-A594	ATTO 594	100 ug	$383	Add to Cart
BHA11910807-5	SPC-789D-ALP	Alkaline Phosphatase	100 ug	$376	Add to Cart
BHA11910807-6	SPC-789D-APC	APC	100 ug	$382	Add to Cart
BHA11910807-7	SPC-789D-BI	Biotin	100 ug	$378	Add to Cart
BHA11910807-8	SPC-789D-FITC	FITC	100 ug	$374	Add to Cart
BHA11910807-9	SPC-789D-HRP	HRP	100 ug	$370	Add to Cart
BHA11910807-10	SPC-789D-PCP	PerCP	100 ug	$382	Add to Cart
BHA11910807-11	SPC-789D-RPE	RPE	100 ug	$380	Add to Cart
BHA11910807-12	SPC-789S	Unconjugated	12 ug	$44	Add to Cart

AKT Antibody - SPC-789

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