May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.
Clonality
polyclonal
Host
Rabbit
Immunogen
ADAM metallopeptidase domain 28
Immunogen Region
ADAM metallopeptidase domain 28
Isotype
IgG
Molecular Weight
35-90 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:200-1:2000
Subcellular Location
Membrane
Synonyms
ADAM 28, ADAM28, eMDC II, eMDCII, MDC L, MDC Lm, MDC Ls, MDCL
Uniprot
Q9UKQ2
Gene Id
10863
Research Area
Developmental biology, Signal Transduction, Metabolism
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:200-1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10453.pdf" target="_blank">Data Sheet</ a>