Mouse Anti-Rat VGLUT1 Monoclonal IgG1

Mfr.No.	SMC-394, SMC-394D, SMC-394D-A390, SMC-394D-A488, SMC-394D-A594, SMC-394D-ALP, SMC-394D-APC, SMC-394D-BI, SMC-394D-FITC, SMC-394D-HRP, SMC-394D-PCP, SMC-394D-RPE, SMC-394S
Immunogen Species	Rat
Alternative Names	BNPI Antibody, SLC17A1 Antibody, SLC17A1/VGLUT1 Antibody, Solute Carrier family 17 member 7 Antibody, Vesicular glutamate transporter 1 Antibody, VGLUT 1 Antibody, Brain-specific Na(+)-dependent inorganic phosphate cotransporter Antibody
Categories	Antibodies
Cellular Localization	Cytoplasmic Vesicle, Secretory Vesicle, Synaptic Vesicle Membrane, Membrane, Cell Junction, Synapse
Certificate Of Analysis	1 ug/ml of SMC-394 was sufficient for detection of VGLut1 in 20 ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Description	Mouse Anti-Rat VGLUT1 Monoclonal IgG1
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1, Rattus Norvegicus (Rat)
Immunogen Region	Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1
Isotype	IgG1
Launch Date	2012/05/16
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Rattus Norvegicus (Rat)
Species Reactivity Medium	Mouse, Rat, Human

Swissprot	Q62634
Accession Number	NP_446311.1
Gene Id	116638
Target	VGLUT1
Clone No	S28-9
Research Area	Cell Markers, Neuron Markers, Presynaptic Markers, Pumps/Transporters, Neurotransmitter Transporters, Cell Signaling, Neuroscience

Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000); optimal dilutions for assays should be determined by the user.
Purification	Protein G Purified
Scientific Background	VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate (1). Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate (2).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~52kDa. No cross-reactivity against VGlut2.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	IHC, WB
Description	WB ; IHC
Dilution	WB (1:1000); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Wojcik S.M., et al. (2004) PNAS. 101(18): 7158-7163. 2. Shigeri Y., Seal R.P., Shimamoto K. (2004) Brain Res Rev. 45(3): 250-265.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11903393-1	SMC-394D	Unconjugated	100 ug	$330	Add to Cart
BHA11903393-2	SMC-394D-A390	ATTO 390	100 ug	$384	Add to Cart
BHA11903393-3	SMC-394D-A488	ATTO 488	100 ug	$383	Add to Cart
BHA11903393-4	SMC-394D-A594	ATTO 594	100 ug	$383	Add to Cart
BHA11903393-5	SMC-394D-ALP	Alkaline Phosphatase	100 ug	$376	Add to Cart
BHA11903393-6	SMC-394D-APC	APC	100 ug	$382	Add to Cart
BHA11903393-7	SMC-394D-BI	Biotin	100 ug	$378	Add to Cart
BHA11903393-8	SMC-394D-FITC	FITC	100 ug	$374	Add to Cart
BHA11903393-9	SMC-394D-HRP	HRP	100 ug	$370	Add to Cart
BHA11903393-10	SMC-394D-PCP	PerCP	100 ug	$382	Add to Cart
BHA11903393-11	SMC-394D-RPE	RPE	100 ug	$380	Add to Cart
BHA11903393-12	SMC-394S	Unconjugated	12 ug	$44	Add to Cart

VGLUT1 Antibody, Clone S28-9 - SMC-394