style=font-size: 9pt; ">This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells."
Host
Mouse
Immunogen
Purified recombinant fragment of Human VCAM1 expressed in E. Coli
Raised In
Mouse
Reactivity
Human
Regulatory
RUO
Relevance
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.
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Species
Homo Sapiens (Human)
Specificity
VCAM1 antibody detects endogenous levels of total VCAM1
Buffer
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 掳C. Stable for 12 months from date of receipt
Description
VCAM1 antibody detects endogenous levels of total VCAM1
Form
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 掳C. Stable for 12 months from date of receipt
Format
liquid
Purification
Affinity-chromatography
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.