Neuron cytoplasmic protein 9.5; PGP 9.5; Ubiquitin thioesterase L1
Categories
Primary Antibodies
Clonality
monoclonal
Description
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity
Host
Mouse
Immunogen
Purified recombinant Human UCHL1. protein fragments expressed in E.coli.
Isotype
IgG2b
Raised In
Mouse
Reactivity
Human
Regulatory
RUO
Relevance
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity
Species
Homo Sapiens (Human)
Specificity
This antibody detects endogenous levels of UCHL1 and does not cross-react with related proteins.
Buffer
Purified mouse monoclonal in PBS(pH 7.4) containing with 0.2% sodium azide, 50% glycerol, 0.1%BSA
Description
This antibody detects endogenous levels of UCHL1 and does not cross-react with related proteins.
Form
Purified mouse monoclonal in PBS(pH 7.4) containing with 0.2% sodium azide, 50% glycerol, 0.1%BSA
Format
liquid
Purification
Affinity purified
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.