Mouse Anti-Rat TrpV3 Monoclonal IgG2a

Mfr.No.	SMC-319, SMC-319D, SMC-319D-A390, SMC-319D-A488, SMC-319D-A594, SMC-319D-ALP, SMC-319D-APC, SMC-319D-BI, SMC-319D-FITC, SMC-319D-HRP, SMC-319D-PCP, SMC-319D-RPE, SMC-319S
Immunogen Species	Rat
Alternative Names	1110036I10Rik Antibody, MGC124324 Antibody, MGC124325 Antibody, Transient receptor potential cation channel subfamily V member 3 Antibody, TrpV3 Antibody, Trpv3 heat sensitive channel Antibody, TRPV3_HUMAN Antibody, Vanilloid receptor 3 Antibody, Vanilloid receptor like 3 Antibody, Vanilloid receptor-like 3 Antibody, vanilloid receptor-related osmotically activated channel protein Antibody, VRL 3,VRL-3 Antibody, VRL3 Antibody
Categories	Antibodies
Cellular Localization	Membrane
Certificate Of Analysis	1 ug/ml of SMC-319 was sufficient for detection of TrpV3 in 10 ug of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Description	Mouse Anti-Rat TrpV3 Monoclonal IgG2a
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide amino acids 774-791 (C-terminus) of rat TrpV3, Rattus Norvegicus (Rat)
Immunogen Region	Synthetic peptide amino acids 774-791 (C-terminus) of rat TrpV3
Isotype	IgG2a
Launch Date	2009/07/06
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Rattus Norvegicus (Rat)
Species Reactivity Medium	Mouse, Rat, Human

Swissprot	Q4QYD9
Accession Number	NP_001020928
Gene Id	497948
Target	TRPV3
Clone No	N15/4
Research Area	Ion Channels, Transient Receptor Potential (TRP) Channels, Neuroscience

Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification	Protein G Purified
Scientific Background	The TRPV3 protein belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels (1, 2).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~70kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, IHC, IP, WB, ICC/IF
Description	WB ; IHC ; ICC ; IF ; IP ; AM
Dilution	WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Masamoto Y., Kawabata F., Fushiki T. (2009) Biosci. Biotechnol. Biochem. 73(5): 1021-1027. 2. Xiao R., et al. (2008) J Biol Chem. 283(10): 6162-6174.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11902804-1	SMC-319D	Unconjugated	100 ug	$330	Add to Cart
BHA11902804-2	SMC-319D-A390	ATTO 390	100 ug	$384	Add to Cart
BHA11902804-3	SMC-319D-A488	ATTO 488	100 ug	$383	Add to Cart
BHA11902804-4	SMC-319D-A594	ATTO 594	100 ug	$383	Add to Cart
BHA11902804-5	SMC-319D-ALP	Alkaline Phosphatase	100 ug	$376	Add to Cart
BHA11902804-6	SMC-319D-APC	APC	100 ug	$382	Add to Cart
BHA11902804-7	SMC-319D-BI	Biotin	100 ug	$378	Add to Cart
BHA11902804-8	SMC-319D-FITC	FITC	100 ug	$374	Add to Cart
BHA11902804-9	SMC-319D-HRP	HRP	100 ug	$370	Add to Cart
BHA11902804-10	SMC-319D-PCP	PerCP	100 ug	$382	Add to Cart
BHA11902804-11	SMC-319D-RPE	RPE	100 ug	$380	Add to Cart
BHA11902804-12	SMC-319S	Unconjugated	12 ug	$44	Add to Cart

TRPV3 Antibody, Clone N15/4 - SMC-319