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Home / Primary Antibodies / Monoclonal Antibodies

Transthyretin

SKU : BHA15100441

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Mfr.No.	AMA93-5M
Clonality	Monoclonal
Description	Transthyretin (TTR), previously called thyroxin-binding Prealbumin, is a 55 kDa homotetramer of 14-15 kDa monomers that is found in plasma. It is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. This protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. These mutations lead to a number of diseases, including amyloidotic polyneuropathy, amyloidotic vitreous opacities, euthyroid hyperthyroxinaemia, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. In Immunohistochemistry of normal tissue, TTR has secretory positivity in plasma and is also found in the liver, the brain, in pancreatic islets and in renal tubules
Host	Mouse
Isotype	IgG2c
Reactivity	Human
Species	Mouse

Clone No	TTR/4292
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-100

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMA93-5M	AMA93-5M	6 mL	$339		Add to Cart
AMA93-10M	AMA93-10M	100 tests - i6000	$637		Add to Cart
AXA93-50D	AXA93-50D	50 tests - Xmatrx	$356		Add to Cart
AXA93-YCD	AXA93-YCD	160 tests - Xmatrx	$871		Add to Cart
MUA93-UC	MUA93-UC	1ml Conc	$696		Add to Cart
MUA93-5UC	MUA93-5UC	0.5ml Conc	$489		Add to Cart

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