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Home / Primary Antibodies / Monoclonal Antibodies

TNFRSF10B Monoclonal Antibody

SKU : BHA10561177

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA584662
Alternative Names	Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L;
Categories	Primary Antibodies
Clonality	monoclonal
Description	Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor.The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.Essential for ER stress-induced apoptosis.
Host	Mouse
Immunogen	Purified recombinant Human TNFRSF10B protein fragments expressed in E.coli.
Isotype	IgG1
Raised In	Mouse
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor.The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.Essential for ER stress-induced apoptosis.
Species	Homo Sapiens (Human)
Specificity	This antibody detects endogenous levels of TNFRSF10B and does not cross-react with related proteins.

Buffer	Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.
Description	This antibody detects endogenous levels of TNFRSF10B and does not cross-react with related proteins.
Form	Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.
Format	liquid
Purification	Affinity purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, ICC

Description

ELISA ; WB ; ICC, WB ; ELISA ; ICC

Dilution

WB	1:500-1:5000
ICC	1:50-1:200

Tested Application

ELISA,WB,ICC;Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10561177	CSB-MA584662	100ul	$384		Add to Cart

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