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Home / Primary Antibodies / Monoclonal Antibodies

TNFR1 antibody

SKU : BHA10808815

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Mfr.No.	FNab08823
Background	Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases(aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse
Immunogen	tumor necrosis factor receptor superfamily, member 1A
Isotype	IgG1
Molecular Weight	50 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	CD120a, FPF, p55, p55 R, p60, TBP1, TBPI, TNF R, TNF R I, TNF R1, TNF R55, TNF Receptor 1, TNF Receptor I, TNF RI, TNFAR, TNFR I, TNFR1, TNFR55, TNFR60, TNFRSF1A

Uniprot	P19438
Clone No	1G4
Research Area	Developmental biology, Immunology, Cardiovascular, Signal Transduction

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, FC
Description	ELISA ; WB ; FC
Tested Application	WB: 1:500-1:5000; IHC: 1:50-1:500

Manual	FNab08823.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808815	FNab08823	100ug	$280		Add to Cart

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