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Home / Primary Antibodies / Monoclonal Antibodies

TFE-3

SKU : BHA15100449

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BioGenex Laboratories

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Mfr.No.	ANB13-5M
Clonality	Monoclonal
Description	Transcription factor E3 (TFE3) is a member of a family of basic helix-loop-helix leucine zipper transcription factors that includes MITF, TFEB, TFE3, and TFEC. Transcription factor binding to IGHM enhancer 3 or transcription factor E3 (TFE3) gene is mapped to human chromosome Xp11.23. In the immune system, TFE3 plays important roles in modulating immunoglobulin heavy-chain expression and regulating B-cell activation. Members of this family form heterodimers with each other, bind the same DNA sequences, and undergo the same types of post-translational modifications; including sumoylation .This gene may be involved in chromosomal translocations that occur in a number of tumors, including sporadic renal cell tumors alveolar soft part sarcoma, perivascular epithelioid cell tumor, and epithelioid hemangioendotheliomas. TFE3 antibody is the most sensitive and specific immunohistochemical marker for the RCC Xp11.2 translocation, which reflects over-expression of the resulting fusion proteins relative to native TFE3.
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	EP285
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
ANB13-5M	ANB13-5M	6 mL	$370		Add to Cart
ANB13-10M	ANB13-10M	100 tests - i6000	$693		Add to Cart
AYB13-50D	AYB13-50D	50 tests - Xmatrx	$390		Add to Cart
AYB13-YCD	AYB13-YCD	160 tests - Xmatrx	$948		Add to Cart
NUB13-UC	NUB13-UC	1ml Conc	$761		Add to Cart
NUB13-5UC	NUB13-5UC	0.5ml Conc	$531		Add to Cart

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