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Home / Primary Antibodies / Monoclonal Antibodies

SMAD2 Monoclonal Antibody

SKU : BHA10561315

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA913719
Alternative Names	hMAD 2; hMAD-2; hSMAD2; JV18 1; JV18; JV18; JV18-1; JV181; MAD; MAD; MAD homolog 2; MAD Related Protein 2; Mad-related protein 2; MADH2; MADR2; MGC22139; MGC34440; Mothers Against Decapentaplegic Homolog 2; Mothers Against Decapentaplegic Homolog 2;
Categories	Primary Antibodies
Clonality	monoclonal
Description	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases.Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and,on formation of the SMAD2/SMAD4 complex,activates transcription.May act as a tumor suppressor in colorectal carcinoma.Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Host	Mouse
Immunogen	Purified recombinant Human SMAD2 protein fragments expressed in E.coli.
Isotype	IgG1
Raised In	Mouse
Reactivity	Human
Regulatory	RUO
Relevance	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases.Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and,on formation of the SMAD2/SMAD4 complex,activates transcription.May act as a tumor suppressor in colorectal carcinoma.Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Species	Homo Sapiens (Human)
Specificity	This antibody detects endogenous levels of SMAD2 and does not cross-react with related proteins.

Buffer	Ascites
Description	This antibody detects endogenous levels of SMAD2 and does not cross-react with related proteins.
Form	Ascites
Format	liquid
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, ICC

Description

ELISA ; WB ; ICC, WB ; ELISA ; ICC

Dilution

WB	1:500-1:5000
ICC	1:50-1:200

Tested Application

ELISA,WB,ICC;Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10561315	CSB-MA913719	100ul	$384		Add to Cart

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