Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
Categories
Primary Antibodies
Clonality
monoclonal
Description
Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
Host
Mouse
Immunogen
RAB27A, member RAS oncogene family
Isotype
IgG1
Molecular Weight
25kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
GS2, GTP binding protein Ram, HsT18676, Rab 27, RAB27, RAB27A, RAM, Ras related protein Rab 27A
Uniprot
P51159
Gene Id
5873
Clone No
9F7
Research Area
Signal Transduction, Neuroscience
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)