Mouse Anti-Human PP5 Monoclonal IgG2a

Mfr.No.	SMC-243, SMC-243D, SMC-243D-A390, SMC-243D-A488, SMC-243D-A594, SMC-243D-ALP, SMC-243D-APC, SMC-243D-BI, SMC-243D-FITC, SMC-243D-HRP, SMC-243D-PCP, SMC-243D-RPE, SMC-243S
Immunogen Species	Human
Alternative Names	PPP5 Antibody, PPT Antibody, Protein phosphatase T Antibody, Serine/threonine protein phosphatase 5 Antibody
Categories	Antibodies
Cellular Localization	Nucleus, Cytoplasm
Certificate Of Analysis	1 ug/ml of SMC-243 was sufficient for detection of PP5 in 15 ug of human A431 lysates by ECL analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Description	Mouse Anti-Human PP5 Monoclonal IgG2a
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Full length human PP5 protein, Homo Sapiens (Human)
Immunogen Region	Full length human PP5 protein
Isotype	IgG2a
Launch Date	2016/09/02
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human

Swissprot	P53041
Accession Number	NP_006238.1
Gene Id	5536
Target	PP5
Clone No	2E11
Research Area	Cell Signaling, Epigenetics and Nuclear Signaling

Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification	Protein G Purified
Scientific Background	Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues, potentially playing a role in the regulation of cell growth and differentiation. PP5 or PPT is predominantly a nuclear protein and interacts with CDC16 and CDC27. It is found in association with several proteins that influence intracellular signlaing-cascades intitiated by hormones (glucocorticoids) or cellular stress (hypoxia, oxidative stress and DNA Damage). It phosphorylates serine residues of skeletal muscle phosphorylase and histone H1. It may also be involved in mitosis and RNA biogenesis regulation (1,2).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~58kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	WB, ICC/IF
Description	WB ; ICC ; IF
Dilution	WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Butzow R., et al. (1988) J Lab Clin Med. 111(2): 249-256.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11902018-1	SMC-243D	Unconjugated	100 ug	$331	Add to Cart
BHA11902018-2	SMC-243D-A390	ATTO 390	100 ug	$385	Add to Cart
BHA11902018-3	SMC-243D-A488	ATTO 488	100 ug	$384	Add to Cart
BHA11902018-4	SMC-243D-A594	ATTO 594	100 ug	$384	Add to Cart
BHA11902018-5	SMC-243D-ALP	Alkaline Phosphatase	100 ug	$377	Add to Cart
BHA11902018-6	SMC-243D-APC	APC	100 ug	$383	Add to Cart
BHA11902018-7	SMC-243D-BI	Biotin	100 ug	$380	Add to Cart
BHA11902018-8	SMC-243D-FITC	FITC	100 ug	$375	Add to Cart
BHA11902018-9	SMC-243D-HRP	HRP	100 ug	$371	Add to Cart
BHA11902018-10	SMC-243D-PCP	PerCP	100 ug	$383	Add to Cart
BHA11902018-11	SMC-243D-RPE	RPE	100 ug	$381	Add to Cart
BHA11902018-12	SMC-243S	Unconjugated	12 ug	$44	Add to Cart

PP5 Antibody, Clone 2E11 - SMC-243