Alkaline phosphatase, placental type is a membrane-bound glycosylated dimeric enzyme, also referred to as the heat-stable form, that is expressed primarily in the placenta, although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. <br><br>PLAP is a tumor marker, especially in seminoma and ovarian cancer. PLAP is reliable only in non-smokers, as smoking interferes with measurement of PLAP, since serum concentrations of PLAP are increased up to 10-fold in smokers and its measurement is therefore of little value in this group. (Wiki)
Formulation
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide
Host
Rabbit
Immunogen Region
A peptide corresponding to the N-terminus of human placental alkaline phosphatase was used as the immunogen for the recombinant PLAP antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
Yes
Subcellular Location
Cytoplasmic, cell membrane
Uniprot
P05187
Clone No
RM317
Format
Purified
Purification
Protein A purified from animal origin-free supeatant