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Home / Primary Antibodies / Monoclonal Antibodies

PE Anti-Mouse IL-17A Antibody[TC11-18H10.1]

SKU : BHA10326335

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1199UD
Background	IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-kB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
Clonality	Monoclonal
Host	Rat
Immunogen	0
Isotype	Rat IgG1, kappa
Reactivity	Mouse

Clone No	TC11-18H10.1
Research Area	Cancer, Immunology

Buffer	PBS with 0.05% Proclin300, 1% BSA
Concentration	0.2 mg/mL
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	ICFCM

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10326335	E-AB-F1199UD	25?g	$90		Add to Cart
BHA10326335	E-AB-F1199UD	50?g	$135		Add to Cart
BHA10326335	E-AB-F1199UD	100?g	$190		Add to Cart
BHA10326335	E-AB-F1199UD	200?g	$320		Add to Cart

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