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Home / Primary Antibodies / Monoclonal Antibodies

PE Anti-Human IL-17A Antibody[BL168]

SKU : BHA10326090

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1173D
Background	IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-kB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively.
Clonality	Monoclonal
Host	Mouse
Immunogen	0
Isotype	Mouse IgG1, kappa
Reactivity	Human

Clone No	BL168
Research Area	Cancer, Immunology

Buffer	PBS with 0.05% Proclin300, 1% BSA
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	ICFCM

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10326090	E-AB-F1173D	20Tests	$75		Add to Cart
BHA10326090	E-AB-F1173D	50Tests	$120		Add to Cart
BHA10326090	E-AB-F1173D	100Tests	$190		Add to Cart
BHA10326090	E-AB-F1173D	200Tests	$285		Add to Cart

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