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Home / Primary Antibodies / Monoclonal Antibodies

PE Anti-Human CD274/PD-L1 Antibody[29E.2A3]

SKU : BHA10325820

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1133D
Background	CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-gamma production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Clonality	Monoclonal
Host	Mouse
Immunogen	0
Isotype	Mouse IgG2b, kappa
Reactivity	Human

Clone No	29E.2A3
Research Area	Cancer, Immunology

Buffer	PBS with 0.05% Proclin300, 1% BSA
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10325820	E-AB-F1133D	20Tests	$75		Add to Cart
BHA10325820	E-AB-F1133D	50Tests	$110		Add to Cart
BHA10325820	E-AB-F1133D	100Tests	$145		Add to Cart
BHA10325820	E-AB-F1133D	200Tests	$220		Add to Cart

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