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Home / Primary Antibodies / Monoclonal Antibodies

OCT4 Monoclonal Antibody

SKU : BHA10564522

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA018403A0m
Alternative Names	POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3), POU5F1, OCT3 OCT4 OTF3
Categories	Primary Antibodies
Clonality	monoclonal
Immunogen	Recombinant Human POU domain, class 5, transcription factor 1 protein (1-360AA)
Isotype	IgG2b
Raised In	Mouse
Reactivity	Human, Mouse, Rat
Relevance	Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Subcellular Location	Cytoplasm, Nucleus

Uniprot	Q01860
Clone No	2H41D8
Database Links	HGNC:9221 OMIM:164177 KEGG:hsa:5460 STRING:9606.ENSP00000259915 UniGene:Hs.249184
Function	Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Pathway	Signaling pathways regulating pluripotency of stem cells
Protein Families	POU transcription factor family, Class-5 subfamily
Tissue Specificity	Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.

Form	Liquid
Purification	>95%, Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Description	IHC ; IF ; WB ; FACS ; ELISA
Tested Application	ELISA, WB, IHC, IF, FC; Recommended dilution: WB:1:500-1:10000, IHC:1:50-1:200, IF:1:50-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Flow Cytometry (FC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10564522	CSB-MA018403A0m	100ul	$350		Add to Cart
BHA10564522	CSB-MA018403A0m	50ul	$210		Add to Cart

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