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Home / Primary Antibodies / Monoclonal Antibodies

MDM2

SKU : BHA15100446

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BioGenex Laboratories

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Mfr.No.	AMB04-5M
Clonality	Monoclonal
Description	MDM2 is a 90kD ubiquitin ligase for p53 and plays a central role in regulation of the stability of p53. MDM2 binds and inhibits transactivation role played by p53 and overexpression of MDM2 can result in the inactivation of p53 and decrease its tumor suppressor function. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. In addition to p53, MDM2 is involved in processes of cell cycle, apoptosis, and tumorigenesis through interactions with proteins that include retinoblastoma 1 and ribosomal protein L5. Further supporting the role of MDM2 as an oncogene, several human tumor types have been shown to have increased levels of MDM2, including soft tissue sarcomas and osteosarcomas as well as breast tumors
Host	Mouse
Isotype	IgG2b
Reactivity	Human
Species	Mouse

Clone No	D-7
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:20-50

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMB04-5M	AMB04-5M	6 mL	$370		Add to Cart
AMB04-10M	AMB04-10M	100 tests - i6000	$693		Add to Cart
AXB04-50D	AXB04-50D	50 tests - Xmatrx	$390		Add to Cart
AXB04-YCD	AXB04-YCD	160 tests - Xmatrx	$948		Add to Cart
MUB04-UC	MUB04-UC	1ml Conc	$761		Add to Cart
MUB04-5UC	MUB04-5UC	0.5ml Conc	$531		Add to Cart

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