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Home / Primary Antibodies / Monoclonal Antibodies

LAG3

SKU : BHA15100339

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BioGenex Laboratories

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Mfr.No.	AW917-50D
Clonality	Monoclonal
Description	LAG-3 (Lymphocyte Activation Gene 3) or CD223 belongs to the Ig superfamily and has high homology to CD4. LAG-3 is an inhibitory T-cell surface molecule that has been found to directly modulate T-cell homeostasis. LAG3 is expressed on populations of activated T cells, such as Tregs and natural killer (NK) cells, and some monocyte-derived cell populations. LAG3 negatively regulates cellular proliferation, activation, and homeostasis of T cells, and has been reported to play a role in Treg suppressive function. LAG3 is often co-expressed with PD-1 on the surface of tumor infiltrating lymphocytes, where the two proteins act independently to synergistically promote tumoral immune escape.
Isotype	IgG
Reactivity	Human

Clone No	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AW917-50D	AW917-50D	6 mL	$387		Add to Cart
AW917-YCD	AW917-YCD	0.5ml Conc	$934		Add to Cart

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