Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides(LPS). Ligand for IL-36R/IL1RL2.
Categories
Primary Antibodies
Clonality
monoclonal
Description
Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
Host
Mouse
Immunogen
interleukin 1 family, member 10(theta)
Isotype
IgG1
Molecular Weight
17 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
FIL1T, IL1HY2, IL38
Uniprot
Q8WWZ1
Gene Id
84639
Clone No
9H1
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)