lang=EN-US" style="font-size: 9pt; font-family: Arial, sans-serif; ">The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene."
Host
Mouse
Immunogen
Purified recombinant fragment of Human IL1B expressed in E. Coli
Raised In
Mouse
Reactivity
Human
Regulatory
RUO
Relevance
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
Species
Homo Sapiens (Human)
Specificity
IL1B antibody detects endogenous levels of total IL1B
Buffer
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20掳C. Stable for 12 months from date of receipt.
Description
IL1B antibody detects endogenous levels of total IL1B
Form
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20°C. Stable for 12 months from date of receipt.
Format
liquid
Purification
Affinity-chromatography
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.