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Home / Primary Antibodies / Monoclonal Antibodies

IDH1

SKU : BHA15100408

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Mfr.No.	AMA22-5M
Clonality	Monoclonal
Description	This antibody identifies a 45kDa protein, which is recognized as isocitrate dehydrogenase (IDH1). It resides to the isocitrate and isopropylmalate dehydrogenases family. Isocitrate dehydrogenase 1 converts a compound called isocitrate to another compound called 2-ketoglutarate in both cytoplasm and peroxisomes. This reaction also release a molecule called NADPH, which is required for other cellular processes. The NADPH produced from isocitrate dehydrogenase 1 is required in the breakdown of fats for energy, and it also safeguard cells from harmful molecules called reactive oxygen species. Recently, an inactivating mutation of IDH1 has been involved in glioblastoma. IDH1 emerges to function as a tumor suppressor that, when inactivated, contributes to tumorigenesis in part through activation of the HIF-1 pathway.
Host	Mouse
Isotype	IgG1 Kappa
Reactivity	Human
Species	Mouse

Clone No	IDH1/1152
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-30

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMA22-5M	AMA22-5M	6 mL	$271		Add to Cart
AMA22-10M	AMA22-10M	100 tests - i6000	$458		Add to Cart
AXA22-50D	AXA22-50D	50 tests - Xmatrx	$285		Add to Cart
AXA22-YCD	AXA22-YCD	160 tests - Xmatrx	$693		Add to Cart
MUA22-UC	MUA22-UC	1ml Conc	$438		Add to Cart
MUA22-5UC	MUA22-5UC	0.5ml Conc	$310		Add to Cart

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