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Home / Primary Antibodies / Monoclonal Antibodies

Histone H3 (Mono Methyl Lys79) Monoclonal Antibody(5G5)

SKU : BHA12101187

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Mfr.No.	BT-MCA0786
Alternative Names	HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b
Categories	Primary Antibodies
Clonality	monoclonal
Description	USP5, also named as ISOT, belongs to the peptidase C19 family. Knock-down of USP5 causes the accumulation of TP53/p53 and an increase in TP53/p53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated TP53/p53 but not with MDM2 for proteasomal recognition. USP5 is a potential target for p53 activating therapeutic agents for the treatment of cancer. It is a novel proteasome associated protein. USP5 cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers.
Formulation	PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Host	Mouse(Mu)
Immunogen	Synthetic Peptide of Histone H3 (Mono Methyl Lys79)
Isotype	IgG2a
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Weight	96 kDa

Concentration	1 mg/ml
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Store at 4°C for a month, for one year store at -20°C. When reconstituted in sterile pH 7.4 0.01 M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-20°C. Avoid repeated freeze/thaw cycles.
Storage Stability	-20°C/1 year

Applications	WB
Description	WB ; ELISA
Dilution	WB: 1:500-2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA12101187	BT-MCA0786	100µl	$226		Add to Cart
BHA12101187	BT-MCA0786	50µl	$110.45		Add to Cart
BHA12101187	BT-MCA0786	20µl	$69.16		Add to Cart

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