Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, and developmental events.
Host
Mouse
Immunogen
Purified recombinant Human HDAC3 protein fragments expressed in E.coli.
Isotype
IgG1
Raised In
Mouse
Reactivity
Rabbit, Human, Mouse, Dog, Pig, Rat
Regulatory
RUO
Relevance
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, and developmental events.
Species
Homo Sapiens (Human)
Buffer
Ascites
Form
Ascites
Format
liquid
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.