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Home / Primary Antibodies / Monoclonal Antibodies

GRB2 Monoclonal Antibody

SKU : BHA10561190

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA148138
Alternative Names	Abundant SRC homology; Adapter protein GRB2; ASH; Ash protein; EGFRBP GRB2; Epidermal growth factor receptor binding protein; Epidermal growth factor receptor binding protein GRB2; GRB 2; GRB2 adapter protein; Grb2; GRB2_HUMAN; Grb3 3;
Categories	Primary Antibodies
Clonality	monoclonal
Description	Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
Host	Mouse
Immunogen	Purified recombinant Human GRB2 protein fragments expressed in E.coli.
Isotype	IgG1
Raised In	Mouse
Reactivity	Monkey, Human, Mouse, Rat
Regulatory	RUO
Relevance	Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
Species	Homo Sapiens (Human)
Specificity	This antibody detects endogenous levels of GRB2 and does not cross-react with related proteins.

Buffer	Ascites
Description	This antibody detects endogenous levels of GRB2 and does not cross-react with related proteins.
Form	Ascites
Format	liquid
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:5000

Tested Application

ELISA,WB;Recommended dilution:WB:1:500-1:5000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10561190	CSB-MA148138	100ul	$384		Add to Cart

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