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Home / Primary Antibodies / Monoclonal Antibodies

GKLF Monoclonal Antibody

SKU : BHA12100779

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Mfr.No.	BT-MCA0699
Alternative Names	KLF4; EZF; GKLF; Krueppel-like factor 4; Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor
Categories	Primary Antibodies
Clonality	monoclonal
Description	SMYD3,also name as ZMYND1 and ZNFN3A1, belongs to the histone-lysine methyltransferase family.It is a histone methyltransferase that plays an important role in transcriptional regulation in human carcinogenesis. It can specifically methylate histone H3 at lysine 4 and activate the transcription of a set of downstream genes, including several oncogenes and genes involved in the control of cell cycle. It plays an important role in transcriptional activation as a member of an RNA polymerase complex. SMYD3 is frequently overexpressed in different types of cancer cells. It functions as a coactivator of Era and potentiates Era activity in response to ligand. SMYD3 as a new coactivator for ER-mediated transcription, providing a possible link between SMYD3 overexpression and breast cancer. The common variable number of tandem repeats polymorphism in SMYD3 is a susceptibility factor for some types of human cancer.
Formulation	Ascitic fluid containing 0.03% sodium azide.
Host	Mouse(Mu)
Immunogen	Purified recombinant fragment of human GKLF expressed in E. Coli.
Isotype	IgG1
Reactivity	Human
Regulatory	RUO

Weight	428aa,49 kDa;369aa,42 kDa

Concentration	1 mg/ml
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Store at 4°C for a month, for one year store at -20°C. When reconstituted in sterile pH 7.4 0.01 M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-20°C. Avoid repeated freeze/thaw cycles.
Storage Stability	-20°C/1 year

Applications	ELISA, IHC-P, IF, WB
Description	WB ; IHC ; ELISA
Dilution	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

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SKU	Supplier No.	Size	Your price	Quantity
BHA12100779	BT-MCA0699	100µl	$226		Add to Cart
BHA12100779	BT-MCA0699	50µl	$110.45		Add to Cart
BHA12100779	BT-MCA0699	20µl	$69.16		Add to Cart

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