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Home / Primary Antibodies / Monoclonal Antibodies

Follicular Dendritic Cell (CD35)

SKU : BHA15100437

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BioGenex Laboratories

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Mfr.No.	AMA78-5M
Clonality	Monoclonal
Description	CD35, also known as complement receptor 1 (CR1), is a 220-300 kDa N-glycosylated member of the RCA (regulators of complement activation) family of proteins. It is a cell membrane-bound, monomeric glycoprotein and its primary function is act as the receptor for complement components C3b and C4b, and it mediates the phagocytosis by neutrophils and monocytes of particles coated with C3b or C4b. CD35 binds and internalizes particles and immune complexes that are opsonized with MBL or complement components C3b, C3i, C4b, or C1q. CD35 additionally protects the cell from complement-mediated lysis by serving as a cofactor for Factor I and inhibiting the C3 and C5 convertases. CD35 is expressed on granulocytes, monocytes, B cells, some NK cells and erythrocytes. CD35 labels follicular dendritic cells of normal and neoplastic origin and is, thus, a useful marker for follicular dendritic cell sarcoma.
Host	Mouse
Isotype	IgG1
Reactivity	Human
Species	Mouse

Clone No	To5
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:20-50

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMA78-5M	AMA78-5M	6 mL	$339		Add to Cart
AMA78-10M	AMA78-10M	100 tests - i6000	$637		Add to Cart
AXA78-50D	AXA78-50D	50 tests - Xmatrx	$356		Add to Cart
AXA78-YCD	AXA78-YCD	160 tests - Xmatrx	$871		Add to Cart
MUA78-UC	MUA78-UC	1ml Conc	$696		Add to Cart
MUA78-5UC	MUA78-5UC	0.5ml Conc	$489		Add to Cart

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