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Home / Primary Antibodies / Monoclonal Antibodies

Factor XIII A

SKU : BHA15100398

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BioGenex Laboratories

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Mfr.No.	AMA11-5M
Clonality	Monoclonal
Description	Factor XIII is a zymogen which is converted into its active form, Factor XIII, by Thrombin. Factor XIII has potentially 2 catalytically active subunits (Factor XIIIa) and 2 inhibitory subunits (Factor XIIIb). Factor XIIIa is a protransglutaminase that belongs to a family of transglutaminases. It catalyzes the formation of covalent cross-links in fibrin. Without Factor XIIIa, a protransglutaminase that belongs to a family of transglutaminases, fibrin is instable and physiologically inadequate. Factor XIIIa consists of 732 amino acids and a molecular mass of 83 kDa. Factor XIIIa is primarily in cells of bone marrow origin. It is present in platelets in large quantities. It is about 3% of total protein content of platelets. Factor 13a is also detected in monocytes. Factor XIII is an important part of the clotting cascade, and its activation is required during the final phase of the clotting cascade when it is activated by thrombin and Ca2+ ions. Fibrin is prominent substrate for Factor XIIIa. Factor XIIIa is a useful marker in differentiating dermatofibroma and dermatofibrosarcoma protuberans, as it is mostly expressed in dermatofibroma.
Host	Mouse
Isotype	IgG1 K
Reactivity	Human
Species	Mouse

Clone No	AC-1A1
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:20-50

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMA11-5M	AMA11-5M	6 mL	$339		Add to Cart
AMA11-10M	AMA11-10M	100 tests - i6000	$582		Add to Cart
AXA11-50D	AXA11-50D	50 tests - Xmatrx	$356		Add to Cart
AXA11-YCD	AXA11-YCD	160 tests - Xmatrx	$871		Add to Cart
MUA11-UC	MUA11-UC	1ml Conc	$526		Add to Cart
MUA11-5UC	MUA11-5UC	0.5ml Conc	$370		Add to Cart

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