Mouse Anti-Human EndoPDI Monoclonal IgG2a

Mfr.No.	SMC-204, SMC-204D, SMC-204D-A390, SMC-204D-A488, SMC-204D-A594, SMC-204D-ALP, SMC-204D-APC, SMC-204D-BI, SMC-204D-FITC, SMC-204D-HRP, SMC-204D-PCP, SMC-204D-RPE, SMC-204S
Immunogen Species	Human
Alternative Names	Thioredoxin domain containing 5; ERP46; UNQ364; MGC3178; FLJ21353; FLJ90810; thioredoxin related protein; endothelial protein disulphide isomeras Antibody
Categories	Antibodies
Cellular Localization	Endoplasmic Reticulum, Endoplasmic Reticulum Lumen
Certificate Of Analysis	1 ug/ml of SMC-204 was sufficient for detection of EndoPDI in 20 ug of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti -mouse IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Description	Mouse Anti-Human EndoPDI Monoclonal IgG2a
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Synthesized peptide - 12 amino acids long (ADGEDGQDPHSK) corresponding to residues 52 - 63 of the EndoPDI protein, Homo Sapiens (Human)
Immunogen Region	Synthesized peptide - 12 amino acids long (ADGEDGQDPHSK) corresponding to residues 52 - 63 of the Human EndoPDI protein
Isotype	IgG2a
Launch Date	2013/04/09
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human

Swissprot	Q8NBS9
Accession Number	NP_001139021
Gene Id	81567
Target	PDI
Clone No	2E7/7
Research Area	Cell Signaling, Chaperone Proteins, Organelle Markers, Protein Trafficking

Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:200); optimal dilutions for assays should be determined by the user.
Purification	Protein G Purified
Scientific Background	Endothelial protein disulfide isomerase (EndoPDI) is a thioredoxin member of the protein disulfide isomerase family of chaperones. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells. EndoPDI mRNA and protein expression is induced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia (1).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~48kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	ELISA, IHC, IP, WB, ICC/IF
Description	WB ; IHC ; ICC ; IF ; IP ; ELISA
Dilution	WB (1:200); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Sullivan D.C., et al. (2003) J Biol Chem. 278 (47) 47079-47088.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11901643-1	SMC-204D	Unconjugated	100 ug	$330	Add to Cart
BHA11901643-2	SMC-204D-A390	ATTO 390	100 ug	$384	Add to Cart
BHA11901643-3	SMC-204D-A488	ATTO 488	100 ug	$383	Add to Cart
BHA11901643-4	SMC-204D-A594	ATTO 594	100 ug	$383	Add to Cart
BHA11901643-5	SMC-204D-ALP	Alkaline Phosphatase	100 ug	$376	Add to Cart
BHA11901643-6	SMC-204D-APC	APC	100 ug	$382	Add to Cart
BHA11901643-7	SMC-204D-BI	Biotin	100 ug	$378	Add to Cart
BHA11901643-8	SMC-204D-FITC	FITC	100 ug	$374	Add to Cart
BHA11901643-9	SMC-204D-HRP	HRP	100 ug	$370	Add to Cart
BHA11901643-10	SMC-204D-PCP	PerCP	100 ug	$382	Add to Cart
BHA11901643-11	SMC-204D-RPE	RPE	100 ug	$380	Add to Cart
BHA11901643-12	SMC-204S	Unconjugated	12 ug	$44	Add to Cart

EndoPDI Antibody, Clone 2E7/7 - SMC-204