Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9K23, and the hair keratins Ha1Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1K8, and the hair keratins, Hb1Hb6. KRT8 is often paired with keratin 18 in vivo.
Categories
Primary Antibodies
Clonality
monoclonal
Description
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT8 is often paired with keratin 18 in vivo.
Host
Mouse
Immunogen
keratin 8
Isotype
IgG2a
Molecular Weight
54 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
CARD2, CK 8, CK8, CYK8, Cytokeratin 8, K2C8, K8, keratin 8, KO, KRT8, Type II keratin Kb8
Antigen
Cytokeratin 8
Uniprot
P05787
Clone No
0C8
Research Area
Developmental biology, Stem Cells, Immunology, Cancer
Weight
54kDa
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)