20 lyase; CP17A_HUMAN; CPT7; CYP17; CYP17A1; CYPXVII; Cytochrome P450 17A1; Cytochrome P450 family 17; Cytochrome P450 family 17 subfamily A polypeptide 1; Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia;
Categories
Primary Antibodies
Clonality
monoclonal
Description
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione.Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.Involved in sexual development during fetal life and at puberty.
Host
Mouse
Immunogen
Purified recombinant Human CYP17A1 protein fragments expressed in E.coli.
Isotype
IgG2b
Raised In
Mouse
Reactivity
Human
Regulatory
RUO
Relevance
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione.Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.Involved in sexual development during fetal life and at puberty.
Species
Homo Sapiens (Human)
Specificity
This antibody detects endogenous levels of CYP17A1 and does not cross-react with related proteins.
Buffer
Ascites
Description
This antibody detects endogenous levels of CYP17A1 and does not cross-react with related proteins.
Form
Ascites
Format
liquid
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.