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Home / Primary Antibodies / Monoclonal Antibodies

Copper Transporting ATPase 2 Antibody, Clone S62-29 - SMC-399

BHA11903488
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+1 866.986.9598
Email
[email protected]
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Swissprot B7ZLR4
Accession Number NP_000044.2
Gene Id 540
Target ATP7B
Clone No S62-29
Research Area Ion Channels, Cell Signaling, Neuroscience
Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration 1 mg/ml
Dilutions WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification Protein G Purified
Scientific Background The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage.
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~160kDa in rat brain membrane preparations.
Storage -20ºC
Storage Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications IHC, IP, WB, ICC/IF
Description WB ; IHC ; ICC ; IF ; IP
Dilution WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Tanzi R.E., et al. (1993) Nature Genetics. 5: 344-350.

2. Ghr/nlm.gov/gene/ATP7B
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11903488-1 SMC-399D Unconjugated 100 ug $330
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BHA11903488-2 SMC-399D-A390 ATTO 390 100 ug $384
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BHA11903488-3 SMC-399D-A488 ATTO 488 100 ug $383
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BHA11903488-4 SMC-399D-A594 ATTO 594 100 ug $383
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BHA11903488-5 SMC-399D-ALP Alkaline Phosphatase 100 ug $376
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BHA11903488-6 SMC-399D-APC APC 100 ug $382
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BHA11903488-7 SMC-399D-BI Biotin 100 ug $378
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BHA11903488-8 SMC-399D-FITC FITC 100 ug $374
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BHA11903488-9 SMC-399D-HRP HRP 100 ug $370
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BHA11903488-10 SMC-399D-PCP PerCP 100 ug $382
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BHA11903488-11 SMC-399D-RPE RPE 100 ug $380
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BHA11903488-12 SMC-399S Unconjugated 12 ug $44
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