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Home / Primary Antibodies / Monoclonal Antibodies

CDK9

SKU : BHA15100333

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BioGenex Laboratories

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Mfr.No.	AN908-5M
Clonality	Monoclonal
Description	CDK9 (Cyclin-dependent kinase 9), is a serine/threonine kinase that forms the catalytic core of the positive transcription elongation factor b (P-TEFb). This enzyme is critical for stimulating transcription elongation of most protein coding genes, including key developmental and stimulus-responsive genes, by RNA polymerase II (RNAPII). CDK9 is not a typical Cdc-2 like kinase and it does not act in cell cycle regulation processes; rather, it acts in differentiation processes. Activity of CDK9 is dependent on binding to a regulatory cyclin subunit (cyclin T1, T2a or T2b) and it is further regulated through association with other modulators like c-myc, NF-kB, androgen receptor (AR) and Brd4. Targeting CDK9 with small molecule inhibitors represents a viable strategy for the treatment of several diseases, indicated especially by the deregulation of CDK9 activity in cancers, cardiac hypertrophy, HIV infections and pathological inflammation. CDK9 inhibitors have demonstrated good antitumoral activity in vitro.
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	K.513.1
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-100

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AN908-5M	AN908-5M	6 mL	$319		Add to Cart
AN908-10M	AN908-10M	100 tests - i6000	$594		Add to Cart
AY908-50D	AY908-50D	50 tests - Xmatrx	$336		Add to Cart
AY908-YCD	AY908-YCD	160 tests - Xmatrx	$815		Add to Cart
NU908-UC	NU908-UC	1ml Conc	$654		Add to Cart
NU908-5UC	NU908-5UC	0.5ml Conc	$458		Add to Cart

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