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Home / Primary Antibodies / Monoclonal Antibodies

BRAP Monoclonal Antibody

SKU : BHA10561147

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA097714
Alternative Names	3010002G07Rik; BRAP2; BRCA1 associated protein; EC 6.3.2.; Galectin 2 binding protein; IMP; Impedes mitogenic signal propagation; Renal carcinoma antigen NY REN 63; RING finger protein 52; RNF52; zgc:92894.
Categories	Primary Antibodies
Clonality	monoclonal
Description	Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Host	Mouse
Immunogen	Purified recombinant Human BRAP protein fragments expressed in E.coli.
Isotype	IgG1
Raised In	Mouse
Reactivity	Human
Regulatory	RUO
Relevance	Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Species	Homo Sapiens (Human)
Specificity	This antibody detects endogenous levels of BRAP and does not cross-react with related proteins.

Clone No	1E7-C9-D10-B10

Buffer	Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Description	This antibody detects endogenous levels of BRAP and does not cross-react with related proteins.
Form	Liquid
Format	liquid
Purification	Affinity purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:5000

Tested Application

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10561147	CSB-MA097714	100ul	$384		Add to Cart

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