JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Monoclonal Antibodies

Biotinylated Anti-CS1 antibody(DM11)?Rabbit mAb

SKU : BHA18100128

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

DIMA Biotechnology

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	DME100011B
Background	Self-ligand receptor of the signaling lymphocytic actIVation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the actIVation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptIVe immune response. ActIVIties are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell actIVation through a SH2D1A-independent eXtracellular signal-regulated ERK-mediated pathway (PubMed:11698418). PositIVely regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536). In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to actIVation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (By similarity). May play a role in lymphocyte adhesion (PubMed:11802771). In LPS-actIVated monocytes negatIVely regulates production of proinflammatory cytokines (PubMed:23695528).
Clonality	Monoclonal
Host	Rabbit
Isotype	Rabbit IgG
Reactivity	Human
Solubility	Flow Cyt 1/100
Synonyms	SLAM7 (19A, CD319, CRACC, CS1)
Usage	Research use only

Form	Powder
Purification	Purified from cell culture supernatant by affinity chromatography
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Applications	Flow Cyt, ELISA

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHA18100128	DME100011B	100 ug	$597		Add to Cart
BHA18100128	DME100011B	10 ug	$90		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.