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Home / Primary Antibodies / Monoclonal Antibodies

APC Anti-Human CD49d Antibody[9F10]

SKU : BHA10325919

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1144E
Background	CD49d is a 150 kD alpha integrin chain known as alpha4 integrin or VLA-4 alpha chain. It forms a heterodimer with either integrin beta1 (alpha4beta1, VLA-4) or beta7 (alpha4beta7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. alpha4beta7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.
Clonality	Monoclonal
Host	Mouse
Immunogen	0
Isotype	Mouse IgG1, kappa
Reactivity	Human

Clone No	9F10
Research Area	Signal transduction, Stem cells, Cancer, Cardiovascular, Immunology

Buffer	PBS with 0.05% Proclin300, 1% BSA
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10325919	E-AB-F1144E	20Tests	$90		Add to Cart
BHA10325919	E-AB-F1144E	50Tests	$145		Add to Cart
BHA10325919	E-AB-F1144E	100Tests	$220		Add to Cart
BHA10325919	E-AB-F1144E	200Tests	$330		Add to Cart

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