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Home / Primary Antibodies / Monoclonal Antibodies

APC Anti-Human CD279/PD-1 Antibody[EH12.2H7]

SKU : BHA10326811

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1229E
Background	Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion., Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Clonality	Monoclonal, Monoclonal
Host	Mouse, Mouse
Immunogen	0, 0
Isotype	Mouse IgG1, kappa
Reactivity	Human, Human

Clone No	EH12.2H7, EH12.2H7

Buffer	PBS with 0.05% Proclin300, 1% BSA, PBS with 0.05% Proclin300, 1% BSA
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze., Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM, FCM

Product Manual	Data Sheet, <a href="https://file.elabscience.com/viewpdf-376701-Elabscience-E-AB-F1229E.pdf" target="_blank">Data Sheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10326811	E-AB-F1229E	20Tests	$85		Add to Cart
BHA10326811	E-AB-F1229E	50Tests	$125		Add to Cart
BHA10326811	E-AB-F1229E	100Tests	$145		Add to Cart
BHA10326811	E-AB-F1229E	200Tests	$220		Add to Cart

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