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Home / Primary Antibodies / Monoclonal Antibodies

Anti-UBR2 Picoband® Antibody (monoclonal, 2G10)

SKU : BHA21003164

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Mfr.No.	M05812, M05812-10ug, M05812-Biotin, M05812-Cy3, M05812-Dylight488, M05812-Dylight550, M05812-Dylight594, M05812-FITC, M05812-HRP, M05812-APC, M05812-PE, M05812-iFluor647, M05812-carrier-free
Alternative Names	tubulin beta class I
Background	E3 ubiquitin-protein ligase UBR2 is an enzyme that in humans is encoded by the UBR2 gene. It is mapped to 6p21.1. This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alteative splicing results in multiple transcript variants.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-UBR2 Picoband® Antibody (monoclonal, 2G10) catalog # M05812. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Host	Mouse
Immunogen Region	E.coli-derived human UBR2 recombinant protein (Position: Q10-A664).
Isotype	Mouse IgG2a
Molecular Weight	202 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Tubulin beta chain; Tubulin beta-5 chain; TUBB; TUBB5; OK/SW-cl.56
Tissue Specificity	Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	Q8IWV8
Gene Id	23304
Gene Name	UBR2
Clone No	Clone: 2G10
Subcellular Location	cytoskeleton

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.25-0.5ug/ml, Human<br>

Reference	1. Kwon, Y. T., Xia, Z., An, J. Y., Tasaki, T., Davydov, I. V., Seo, J. W., Sheng, J., Xie, Y., Varshavsky, A. Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway. Molec. Cell. Biol. 23: 8255-8271, 2003.<br /><br />2. Nagase, T., Ishikawa, K., Nakajima, D., Ohira, M., Seki, N., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 4: 141-150, 1997.<br /><br />3. Yin, J., Kwon, Y. T., Varshavsky, A., Wang, W. RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Hum. Molec. Genet. 13: 2421-2430, 2004.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003164-1	M05812	-	100 ug	$370		Add to Cart
BHA21003164-2	M05812-10ug	Sample	10 ug	$99		Add to Cart
BHA21003164-3	M05812-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003164-4	M05812-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003164-5	M05812-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003164-6	M05812-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003164-7	M05812-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003164-8	M05812-FITC	FITC	100 ug	$570		Add to Cart
BHA21003164-9	M05812-HRP	HRP	100 ug	$570		Add to Cart
BHA21003164-10	M05812-APC	APC	100 ug	$670		Add to Cart
BHA21003164-11	M05812-PE	PE	100 ug	$670		Add to Cart
BHA21003164-12	M05812-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003164-13	M05812-carrier-free	carrier-free	100 ug	$370		Add to Cart

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