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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Tropomyosin(36/39 kDa) Tpm1 Antibody (Monoclonal, TM31)

SKU : BHA21006562

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Mfr.No.	MA1095
Alternative Names	Tropomyosin alpha-1 chain
Background	The tropomyosins are a family of actin filament binding proteins. These proteins were first isolated from skeletal muscle, but later identified in many nonmuscle tissues. Tropomyosins are ubiquitous proteins of 35 to 45 kD associated with the actin filaments of myofibrils and stress fibers. Vertebrates have at least 4 different tropomyosin genes; in humans, they are named TPM1, TPM2, TPM3, and TPM4. Tropomyosins expressed as different isoforms in muscle and non-muscle cells.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Tropomyosin (36/39 kDa) Tpm1 Antibody (Monoclonal, TM31) catalog # MA1095. Tested in WB applications. This antibody reacts with Chicken, Human, Mouse, Rat.
Function	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction w
Host	Mouse
Immunogen Region	Chicken gizzard tropomyosin.
Isotype	Mouse IgG1
Molecular Weight	35-45 kDa
Reactivity	Chicken, Human, Mouse, Rat
Reconstitution	Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Tropomyosin alpha-1 chain;Alpha-tropomyosin;Tropomyosin-1;Tpm1;Alpha-tm, Tpma;
Tissue Specificity	TPM1: Detected in primary breast cancer tissues butundetectable in normal breast tissues in Sudanese patients.Isoform 1 is expressed in adult and fetal skeletal muscle andcardiac tissues, with higher expression levels in the cardiactissues. Isoform 10 is expressed in adult and fetal cardiactissues, but not in skeletal muscle.
Note	Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Uniprot	P04692
Gene Id	Human(7168), Mouse(22003), Rat(24851)
Gene Name	TPM1
Clone No	Clone: TM31
Sequence	Belongs to the tenascin family.
Subcellular Location	Cytoplasm, cytoskeleton.

Concentration	Adding 1 ml of PBS buffer will yield a concentration of 100 ug/ml.
Form	Lyophilized
Purification	Ascites
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.5-1ug/ml, Human, mouse, rat, chicken<br>

Reference	1. Lees-Miller, J. P.; Helfman, D. M. : The molecular basis for tropomyosin isoform diversity. BioEssays 13: 429-437, 1991. <br /><br />2. Gariboldi, M.; Manenti, G.; Dragani, T. A.; Pierotti, M. A. : Chromosome mapping of nine tropomyosin-related sequences in mice. Mammalian Genome 6: 273-277, 1995.<br /><br /><br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006562-1	MA1095	-	100 ug	$370		Add to Cart

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