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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Transferrin/TF Antibody Picoband® (monoclonal, 7I11B10)

SKU : BHA21004830

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Mfr.No.	M00094-5, M00094-5-10ug, M00094-5-Biotin, M00094-5-Cy3, M00094-5-Dylight488, M00094-5-Dylight550, M00094-5-Dylight594, M00094-5-FITC, M00094-5-HRP, M00094-5-APC, M00094-5-PE, M00094-5-iFluor647, M00094-5-carrier-free
Alternative Names	high mobility group box 1
Background	Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. In humans, it is encoded by the TF gene. Transferrin consists of a polypeptide chain containing 679 amino acids in humans. The protein is composed of alpha helices and beta sheets to form two domains. The N- and C- terminal sequences are represented by globular lobes and between the two lobes is an iron-binding site. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of tuover (25 mg/24 h). And Transferrin has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe(III) binding sites. The affinity of transferrin for Fe(III) is extremely high (1023 M1 at pH 7.4) but decreases progressively with decreasing pH below neutrality.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Transferrin/TF Antibody Picoband® (monoclonal, 7I11B10) catalog # M00094-5. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remod
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human Transferrin, different from the related mouse and rat sequences by five amino acids.
Isotype	IgG2b
Molecular Weight	77 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	High mobility group protein B1; High mobility group protein 1; HMG-1; HMGB1; HMG1
Tissue Specificity	Ubiquituous. Expressed in platelets.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P02787
Gene Id	7018
Gene Name	TF
Clone No	Clone: 7I11B10
Subcellular Location	Nucleus. Endosome. Secreted. Cell membrane. Peripheral membrane protein. Extracellular side. Chromosome. Cytoplasm. Endoplasmic reticulum-Golgi intermediate compartment.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat

Reference	1. Asada-Senju, M., Maeda, T., Sakata, T., Hayashi, A., Suzuki, T.Molecular analysis of the transferrin gene in a patient with hereditary hypotransferrinemia.J. Hum. Genet. 47: 355-359, 2002. 2. Delanghe, J., Verstraelen, H., Pynaert, I., Debels, L., Taes, Y., Verhasselt, B., De Henauw, S., Temmerman, M.Human transferrin G277S mutation and iron deficiency in pregnancy. (Letter)Brit. J. Haemat. 132: 249-250, 2005. 3. Pang, H., Koda, Y., Soejima, M., Kimura, H.Identification of a mutation (A1879G) of transferrin from cDNA prepared from peripheral blood cells.Ann. Hum. Genet. 62: 271-274, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004830-1	M00094-5	-	100 ug	$370		Add to Cart
BHA21004830-2	M00094-5-10ug	Sample	10 ug	$99		Add to Cart
BHA21004830-3	M00094-5-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004830-4	M00094-5-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004830-5	M00094-5-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004830-6	M00094-5-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004830-7	M00094-5-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004830-8	M00094-5-FITC	FITC	100 ug	$570		Add to Cart
BHA21004830-9	M00094-5-HRP	HRP	100 ug	$570		Add to Cart
BHA21004830-10	M00094-5-APC	APC	100 ug	$670		Add to Cart
BHA21004830-11	M00094-5-PE	PE	100 ug	$670		Add to Cart
BHA21004830-12	M00094-5-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004830-13	M00094-5-carrier-free	carrier-free	100 ug	$370		Add to Cart

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