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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Toll-like Receptor 3 Monoclonal Antibody

SKU : BHA13600131

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Beijing Solarbio Science & Technology Co., Ltd.

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Mfr.No.	K000177M
Alternative Names	CD283 ; IIAE2
Background	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse(Mu)
Immunogen	Purified recombinant human Toll-Like Receptor 3 protein fragments expressed in E.coli.
Isotype	IgG2b
Molecular Weight	According to the fused protein
Promotion	By one Solarbio antibody to get same size loading control/tag antibody for free. Click here to read more
Subcellular Location	Early endosome Endoplasmic reticulum membrane Endosome membrane Single-pass type I membrane protein

Swissprot	O15455
Gene Id	7098
Gene Name	Toll-like Receptor 3
Clone No	2F10-B8-G9

Purification	Affinity purification
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications	WB
Dilution	WB 1:1000.

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SKU	Supplier No.	Size	Your price	Quantity
BHA13600131	K000177M	50µl	$278.89		Add to Cart
BHA13600131	K000177M	100µl	$356.67		Add to Cart

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