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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Thioredoxin 2/TXN2 Antibody Picoband® (monoclonal, 4H3)

SKU : BHA21002602

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Mfr.No.	M04586-2, M04586-2-10ug, M04586-2-Biotin, M04586-2-Cy3, M04586-2-Dylight488, M04586-2-Dylight550, M04586-2-Dylight594, M04586-2-FITC, M04586-2-HRP, M04586-2-APC, M04586-2-PE, M04586-2-iFluor647, M04586-2-carrier-free
Alternative Names	thioredoxin 2
Background	Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the TXN2 gene on chromosome 22. It is mapped to 22q12.3. This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Thioredoxin 2/TXN2 Antibody Picoband® (monoclonal, 4H3) catalog # M04586-2. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.
Host	Mouse
Immunogen Region	E.coli-derived human Thioredoxin 2/TXN2 recombinant protein (Position: T60-G166).
Isotype	Mouse IgG2a
Molecular Weight	14 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Thioredoxin, mitochondrial; MTRX; Mt-Trx; Thioredoxin-2; TXN2; TRX2
Tissue Specificity	Widely expressed in adult (at protein level) and fetal tissues.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	Q99757
Gene Id	25828
Gene Name	TXN2
Clone No	Clone: 4H3
Subcellular Location	Mitochondrion.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat<br> Immunofluorescence, 2ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Benhar, M., Forrester, M. T., Hess, D. T., Stamler, J. S. Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science 320: 1050-1054, 2008.<br /><br />2. Chen, Y., Cai, J., Murphy, T. J., Jones, D. P. Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells. J. Biol. Chem. 277: 33242-33248, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002602-1	M04586-2	-	100 ug	$370		Add to Cart
BHA21002602-2	M04586-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21002602-3	M04586-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002602-4	M04586-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002602-5	M04586-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002602-6	M04586-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002602-7	M04586-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002602-8	M04586-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21002602-9	M04586-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21002602-10	M04586-2-APC	APC	100 ug	$670		Add to Cart
BHA21002602-11	M04586-2-PE	PE	100 ug	$670		Add to Cart
BHA21002602-12	M04586-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002602-13	M04586-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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