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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Spectrin(Alpha And Beta) SPTB Antibody (Monoclonal, SB-SP1)

SKU : BHA21006557

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Mfr.No.	MA1090
Alternative Names	spectrin, alpha, erythrocytic 1(elliptocytosis 2); spectrin, beta, erythrocytic
Background	Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2. Spectrin mutations cause spinocerebellar ataxia type 5.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Spectrin (Alpha And Beta) SPTB Antibody (Monoclonal, SB-SP1) catalog # MA1090. Tested in WB applications. This antibody reacts with Human.
Function	SPTA1: Spectrin is the major constituent of the cytoskeletalnetwork underlying the erythrocyte plasma membrane. It associateswith band 4.1 and actin to form the cytoskeletal superstructure ofthe erythrocyte plasma membrane.\|SPTB: Spectrin is the major con
Host	Mouse
Immunogen Region	Human erythrocyte spectrin.
Isotype	Mouse IgG1
Molecular Weight	60 kDa
Reactivity	Human
Reconstitution	Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Erythroid spectrin beta ;Sptb ;LOC314251 ;
Note	Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Uniprot	Q6XDA0
Gene Id	Human(6708), Mouse(20739), Rat(289257), Human(6710), Mouse(20741), Rat(314251)
Gene Name	SPTA1; SPTB
Clone No	Clone: SB-SP1
Sequence	Belongs to the spectrin family.
Subcellular Location	SPTA1: Cytoplasm, cytoskeleton. Cytoplasm, cellcortex.\|Spta1: Cytoplasm, cytoskeleton. Cytoplasm, cellcortex.\|SPTB: Cytoplasm, cytoskeleton. Cytoplasm, cellcortex.\|Sptb: Cytoplasm, cytoskeleton. Cytoplasm, cellcortex.

Concentration	Adding 1 ml of PBS buffer will yield a concentration of 100 ug/ml.
Form	Lyophilized
Purification	Ascites
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 2-4ug/ml, Human<br>

Reference	1. Watkins, P. C.; Eddy, R.; Forget, B. G.; Chang, J. G.; Rochelle, R.; Shows, T. B. : Assignment of a non-erythroid spectrin gene to human chromosome 2. (Abstract) Am. J. Hum. Genet. 43: A161, 1988. <br /><br />2. Ikeda, Y.; Dick, K. A.; Weatherspoon, M. R.; Gincel, D.; Armbrust, K. R.; Dalton, J. C.; Stevanin, G.; Durr, A.; Zuhlke, C.; Burk, K.; Clark, H. B.; Brice, A.; Rothstein, J. D.; Schut, L. J.; Day, J. W.; Ranum, L. P. W. : Spectrin mutations cause spinocerebellar ataxia type 5. Nature Genet. 38: 184-190, 2006.<br /><br /><br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006557-1	MA1090	-	100 ug	$370		Add to Cart

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