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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Sorbitol Dehydrogenase/SORD Antibody Picoband® (monoclonal, 12B10G2)

SKU : BHA21004089

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Mfr.No.	M07851-1, M07851-1-10ug, M07851-1-Biotin, M07851-1-Cy3, M07851-1-Dylight488, M07851-1-Dylight550, M07851-1-Dylight594, M07851-1-FITC, M07851-1-HRP, M07851-1-APC, M07851-1-PE, M07851-1-iFluor647, M07851-1-carrier-free
Alternative Names	chaperonin containing TCP1 subunit 3
Background	Sorbitol dehydrogenase is an enzyme that in humans is encoded by the SORD gene. Sorbitol dehydrogenase (SORD) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Sorbitol Dehydrogenase/SORD Antibody Picoband® (monoclonal, 12B10G2) catalog # M07851-1. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vi
Host	Mouse
Immunogen Region	E.coli-derived human Sorbitol Dehydrogenase/SORD recombinant protein (Position: N8-P357).
Isotype	Mouse IgG1
Molecular Weight	40 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	T-complex protein 1 subunit gamma; TCP-1-gamma; CCT-gamma; hTRiC5; CCT3; CCTG; TRIC5
Tissue Specificity	Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q00796
Gene Id	6652
Gene Name	SORD
Clone No	Clone: 12B10G2
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Rat<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Carr, I. M., Markham, A. F., Coletta, P. L. Identification and characterisation of a sequence related to human sorbitol dehydrogenase. Europ. J. Biochem. 245: 760-767, 1997. <br /><br />2. Carr, I. M., Markham, A. F. Molecular genetic analysis of the human sorbitol dehydrogenase gene. Mammalian Genome 6: 645-652, 1995.<br /><br />3. Carr, I. M., Whitehouse, A., Coletta, P. L., Markham, A. F. Structural and evolutionary characterization of the human sorbitol dehydrogenase gene duplication. Mammalian Genome 9: 1042-1048, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004089-1	M07851-1	-	100 ug	$370		Add to Cart
BHA21004089-2	M07851-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21004089-3	M07851-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004089-4	M07851-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004089-5	M07851-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004089-6	M07851-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004089-7	M07851-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004089-8	M07851-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21004089-9	M07851-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21004089-10	M07851-1-APC	APC	100 ug	$670		Add to Cart
BHA21004089-11	M07851-1-PE	PE	100 ug	$670		Add to Cart
BHA21004089-12	M07851-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004089-13	M07851-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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