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Home / Primary Antibodies / Monoclonal Antibodies

Anti-RUNX2 Monoclonal Antibody

SKU : BHA21008802

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Mfr.No.	M00442, M00442-30ul
Alternative Names	Death domain-associated protein 6
Clonality	Monoclonal
Description	Boster Bio Anti-RUNX2 Monoclonal Antibody catalog # M00442. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Function	Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartmen
Host	Rabbit
Immunogen Region	A synthesized peptide derived from human RUNX2.
Isotype	Rabbit IgG
Molecular Weight	57 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Synonyms	Death domain-associated protein 6;Daxx;hDaxx;ETS1-associated protein 1;EAP1;Fas death domain-associated protein;DAXX;BING2, DAP6;
Tissue Specificity	Ubiquitous.
Note	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Uniprot	Q13950
Gene Name	RUNX2
Clone No	Clone: HCO-18
Subcellular Location	Cytoplasm. Nucleus, nucleoplasm. Nucleus, PML body . Nucleus, nucleolus. Chromosome, centromere. Dispersed throughout the nucleoplasm, in PML/POD/ND10 nuclear bodies, and in nucleoli. Colocalizes with histone H3.3, ATRX, HIRA and ASF1A at PML-nuclear bodies. Colocalizes with a subset of interphase centromeres, but is absent from mitotic centromeres. Detected in cytoplasmic punctate structures. Translocates from the nucleus to the cytoplasm upon glucose deprivation or oxidative stress. Colocalizes with RASSF1 in the nucleus. Colocalizes with USP7 in nucleoplasma with accumulation in speckled structures.

Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form	Liquid
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, ICC, WB
Description	WB 1:500-1:2000 IHC 1:100-1:500 ICC/IF 1:50-1:200

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21008802-1	M00442	-	100 ul	$370		Add to Cart
BHA21008802-2	M00442-30ul	Sample	30 ul	$99		Add to Cart

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