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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband® (monoclonal, 4F3)

SKU : BHA21002589

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Mfr.No.	M04147, M04147-10ug, M04147-Biotin, M04147-Cy3, M04147-Dylight488, M04147-Dylight550, M04147-Dylight594, M04147-FITC, M04147-HRP, M04147-APC, M04147-PE, M04147-iFluor647, M04147-carrier-free
Alternative Names	ribonuclease/angiogenin inhibitor 1
Background	Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular Rnases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the tuover of RNA in eukaryotic cells, RNH may be essential for control of mRNA tuover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband® (monoclonal, 4F3) catalog # M04147. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human RNH1, different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.
Isotype	Mouse IgG2b
Molecular Weight	45 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	AW546468 antibody; C80305 antibody; MGC18200 antibody; MGC4569 antibody; MGC54054 antibody; OTTHUMP00000147628 antibody; OTTHUMP00000229864 antibody; OTTHUMP00000229865 antibody; OTTHUMP00000229866 antibody; OTTHUMP00000229870 antibody; OTTHUMP00000229871 antibody; OTTHUMP00000229872 antibody; Placental ribonuclease inhibitor antibody; Placental RNase inhibitor antibody; PRI antibody; RAI antibody; RI antibody; Ribonuclease inhibitor antibody; Ribonuclease/angiogenin inhibitor 1 antibody; Ribonuclease/angiogenin inhibitor antibody; RINI_HUMAN antibody; RNase inhibitor antibody; RNH 1 antibody; RNH antibody; RNH1 antibody; Rnh1 ribonuclease/angiogenin inhibitor 1 antibody
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P13489
Gene Id	6050
Gene Name	RNH1
Clone No	Clone: 4F3
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.1-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. "Entrez Gene: RNH1 ribonuclease/angiogenin inhibitor 1".<br /><br />2. Weremowicz S, Fox EA, Morton CC, Vallee BL (1991). "The placental ribonuclease inhibitor (RNH) gene is located on chromosome subband 11p15.5.". Genomics 8(4): 71721.<br /><br />3. Zneimer SM, Crawford D, Schneider NR, Beutler B (1991). "Mapping of the human ribonuclease inhibitor gene (RNH) to chromosome 11p15 by in situ hybridization.". Genomics 8 (1): 1758.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002589-1	M04147	-	100 ug	$370		Add to Cart
BHA21002589-2	M04147-10ug	Sample	10 ug	$99		Add to Cart
BHA21002589-3	M04147-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002589-4	M04147-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002589-5	M04147-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002589-6	M04147-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002589-7	M04147-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002589-8	M04147-FITC	FITC	100 ug	$570		Add to Cart
BHA21002589-9	M04147-HRP	HRP	100 ug	$570		Add to Cart
BHA21002589-10	M04147-APC	APC	100 ug	$670		Add to Cart
BHA21002589-11	M04147-PE	PE	100 ug	$670		Add to Cart
BHA21002589-12	M04147-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002589-13	M04147-carrier-free	carrier-free	100 ug	$370		Add to Cart

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